This guide contains information about places where you can stop for the night when driving from
Tupelo, Mississippi to Myrtle Beach, South Carolina.
Total distance for the trip is around 643 miles with a driving time of approximately 9 hours 29 mins.
Cities and towns with hotels that are on the fastest route between Tupelo and Myrtle Beach
are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)
134 miles from Tupelo (1 hour 59 mins)
508 miles from Myrtle Beach (7 hours 34 mins)
279 miles from Tupelo (4 hours 6 mins)
362 miles from Myrtle Beach (5 hours 28 mins)
424 miles from Tupelo (6 hours 11 mins)
223 miles from Myrtle Beach (3 hours 35 mins)
493 miles from Tupelo (7 hours 6 mins)
153 miles from Myrtle Beach (2 hours 33 mins)
571 miles from Tupelo (8 hours 13 mins)
67.3 miles from Myrtle Beach (1 hour 19 mins)
